卒中相关性肺炎的病原菌特点及危险因素分析

作者:吴志元;黄振华;钟守磊;黄金凤;黄玉华 刊名:广东医科大学学报 上传者:孙昊天

【摘要】目的 探讨卒中相关性肺炎(SAP)的病原菌特点及危险因素.方法 选取我科收治的600例脑卒中患者作为研究对象,根据是否发生SAP将其分为SAP组和对照组.分析SAP的病原菌特点和危险因素.结果 在92例SAP患者中检出15种病原菌,以革兰阴性菌为主,占76.1%(70/92).多因素Logistic回归分析显示意识障碍、吞咽困难、APACHE Ⅱ评分>25分、机械通气>7 d、入住ICU时间>3 d和糖尿病与SAP相关(P<0.05或0.01).结论 鲍曼不动杆菌是SAP最常见的病原菌.SAP的独立危险因素包括意识障碍、吞咽困难、APACHEⅡ评分>25分、机械通气>7 d、入住ICU时间>3 d和糖尿病.

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第36卷第4期 广东医科大学学报 v01.36 No.4 2018年8月 J0uRNAL 0F GuANGDONG MEDIcAL uNIVERsITY A-ug.2018 43 l 卒中相关性肺炎的病原茵特点及危险因素分析 吴志元,黄振华,钟守磊,黄金凤,黄玉华 (广东省廉江市人民医院神经内科,广东廉江524400) 摘要:目的探讨卒中相关性肺炎(sAP)的病原菌特点及危险因素。方法选取我科收治的600例脑卒中患者作为 研究对象,根据是否发生sAP将其分为SAP组和对照组。分析sAP的病原菌特点和危险因素。结果在92例sAP患者中 检出15种病原菌,以革兰阴性菌为主,占76.1%(70/92)。多因素Logistic回归分析显示意识障碍、吞咽困难、 APAcHEⅡ评分>25分、机械通气>7 d、人住Icu时间>3 d和糖尿病与sAP相关(P<o.05或o。01)。结论鲍曼不动杆菌是 sAP最常见的病原菌。sAP的独立危险因素包括意识障碍、吞咽困难、APAcHEⅡ评分>25分、机械通气>7 d、入住 ICU时间>3 d和糖尿病。 关键词:卒中相关性肺炎;病原菌;危险因素 中图分类号:R 587.1 文献标志码:A 文章编号:2096.3610f2018)04.0431.04 Study on the characteristics of pathogenic bacteria and risk factors of stroke associated pneumonla WU Zhi—yuan,HUANG Zhen-hua,ZHONG Shou—lei,HUANG Jin-feng,HUANG 1m-hua(Depanment of Neurology, me Lianjiang People’s Hospital,Lianjiang 524400,China) Abstract:Obiec“ve To investigate the characteristics of pathogenic bacteria and risk factors of stroke associated pneumonia.Methods A total of 600 stroke patients admitted to our departmem were selected as the subjects and randomly divided into SAP Group aIld Non,SAP Gmup based on whether there is SAP.The characteristics of pathogenic bacteria and risk factors of SAP were analyzed.ResuIts Among the 92 patients with SAP,1 5 kinds of pathogenic bacteria were detected, mainly gram—negative bacteria (70/92, 76.1%). MultiVariable 109istic regression analysis showed disturbance of consciousness,dysphagia,APACHEⅡscore of>25 points,mechanical ventilation of>7 d,ICU stay of>3 d and correlation of diabetes

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