老年肺癌患者CT多期增强扫描的影像学特征与特异性标记物表达相关性及联合诊断价值

作者:王磊;刘伟;黄晓日 刊名:中国老年学杂志 上传者:王超

【摘要】目的研究老年肺癌患者CT多期增强扫描的影像学特征与血清特异性肿瘤标记物表达的相关性以及联合诊断价值。方法随机选择2013年4月至2015年11月该院收治的肺癌患者54例作为观察组,另选同期治疗的肺部良性病变患者50例作为对照组。分别对两组患者进行CT多期增强扫描和特异性标记物表达水平检测。结果观察组患者肺动脉期、主动脉期、延迟期CT增强值均显著高于对照组(P〈0.05)。观察组患者3期CT增强值之间差异显著(F=41.071,P〈0.05),对照组患者3期CT增强值之间无统计学差异(F=8.065,P〉0.05)。观察组患者血清癌胚抗原(CEA)、细胞角质素片段抗原(CYFRA)21-1以及神经元特异性烯醇化酶(NSE)水平均显著高于对照组(P〈0.05)。联合诊断对老年肺癌诊断的灵敏度和特异性分别为91.4%和92.2%。结论老年肺癌患者CT多期增强扫描的影像学特征与血清特异性肿瘤标记物表达呈现良好的相关性,二者联合诊断可有效提高对老年肺癌诊断的灵敏度和特异性。

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