Neural stem cells as novel cancer therapeutic vehicles

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【作者】 Stephen Yip  Roya Sabetrasekh  Richard L. Sidman and Evan Y. Snyder 

【关键词】Neural stem cells  Stem cells  Oncogenesis  Intracranial neoplasms  Gliomas  Glioblastoma multiforme  Gene therapy  Migration 


【摘要】The startling resemblance of many of the behaviours of brain tumours to the intrinsic properties of the neural stem/progenitor cell has triggered a recent dual interest in arming stem cells to track and help eradicate tumours and in viewing stem cell biology as somehow integral to the emergence and/or propagation of the neoplasm itself. These aspects are reviewed and discussed here.

【刊名】European Journal of Cancer